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A Study to Learn if Itraconazole Changes How the Body Processes PF-07248144 (Study Medicine)

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NCT07335419

Sponsored by Pfizer (industry) · PFE — their whole pipeline →.

Phase
Phase 1
Status
Active, not recruiting
Study type
Interventional
Design
Non randomized · None · Basic science
Enrollment
12actual
Sites
1
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-01-02actualWhen the study began enrolling
Primary completion2026-02-22actualThe date the last participant is measured for the primary outcome — the readout window
Study completion2026-03-21estimatedThe whole study's end, after follow-up
First posted2026-01-13actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-03-19actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Healthy Adult Participants

Interventions

  • Drug: PF-07248144
  • Drug: Itraconazole

Primary outcomes

what the primary-completion date above is the date OF
Area under the concentration-time curve from time zero to extrapolated infinite time (AUCinf) for PF-07248144
measured 0 (pre-dose), 0.5, 1, 1.5, 2, 3, 4, 6, 8, 12, 24, 36, 48, 72, 120, 168, and 216 hours post-dose
Area under the concentration-time curve from time zero to time of last measurable concentration (AUClast) for PF-07248144
measured 0 (pre-dose), 0.5, 1, 1.5, 2, 3, 4, 6, 8, 12, 24, 36, 48, 72, 120, 168, and 216 hours post-dose
Maximum observed plasma concentration (Cmax) for PF-07248144
measured 0 (pre-dose), 0.5, 1, 1.5, 2, 3, 4, 6, 8, 12, 24, 36, 48, 72, 120, 168, and 216 hours post-dose

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