A Study of ASP2246 for People Who Have Movement Problems Caused by Brain Injury After a Stroke
← catalyst calendarNCT07318714 · readout in 1,288 d
Sponsored by Astellas Pharma Inc (industry) · 4503.T — their whole pipeline →.
Phase
Phase 1/2
Status
Recruiting
Study type
Interventional
Design
Randomized · Double · Treatment
Enrollment
84estimated
Sites
5
Country
Japan
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2026-04-03 | actual | When the study began enrolling |
| Primary completion | 2030-02-28 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2030-02-28 | estimated | The whole study's end, after follow-up |
| First posted | 2026-01-06 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-07-09 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Chronic Ischemic Stroke
Interventions
- Drug: ASP2246
- Procedure: Brain surgery
- Procedure: Sham surgery
- Other: Rehabilitation therapy
Primary outcomes
what the primary-completion date above is the date OFNumber of participants with Dose-Limiting Toxicity (DLT)
measured Up to 2 Weeks
Number of participants with Treatment-Emergent Adverse Events (TEAEs)
measured Up to 52 Weeks
Number of participants with Serious Adverse Events (SAEs)
measured Up to 52 Weeks
Number of participants with an Adverse Event of Special Interest (AESI)
measured Up to 52 Weeks
Number of Participants with Suicidal Ideation and/or Behavior as Assessed by Columbia-Suicide Severity Rating Scale (C-SSRS)
measured Up to 52 Weeks
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