A Trial to Compare the Extent to Which Maridebart Cafraglutide (AMG 133) is Made Available in the Body When Administered Using Two Subcutaneous Presentations
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Phase
Phase 1
Status
Completed
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
349actual
Sites
4
Country
United States
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2025-12-15 | actual | When the study began enrolling |
| Primary completion | 2026-07-02 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2026-07-02 | actual | The whole study's end, after follow-up |
| First posted | 2026-01-02 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-08-07 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Overweight and Obesity
Intervention
- Drug: Maridebart Cafraglutide — also filed as AMG 133
Primary outcomes
what the primary-completion date above is the date OFArea Under the Plasma Concentration-time Curve (AUC) From Time 0 to Infinity (AUCinf) of AMG 133
measured Up to Day 120
AUC From Time 0 to the Time of the Last Quantifiable Concentration (AUClast) of AMG 133
measured Up to Day 120
Maximum Observed Plasma Concentration (Cmax) of AMG 133
measured Up to Day 120
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