A 2-part, Phase 1b Clinical Study Designed to Evaluate the Safety, PK, and Efficacy of CRB-913 in Participants With Obesity

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NCT07310901

Sponsored by Corbus Pharmaceuticals Inc. (industry) · CRBP — their whole pipeline →.

Phase

Phase 1

Status

Active, not recruiting

Study type

Interventional

Design

Randomized · Double · Treatment

Enrollment

252estimated

Sites

Country

United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis

Date

Filed

Basis

What it is

Start

2025-12-04

actual

When the study began enrolling

Primary completion

2026-07-02

estimated

The date the last participant is measured for the primary outcome — the readout window

Study completion

2026-07-31

estimated

The whole study's end, after follow-up

First posted

2025-12-30

actual

When this record first appeared on the registry

Results posted

—

When the sponsor posted results to the registry

Record updated

2026-05-29

actual

The sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

Obese But Otherwise Healthy Participants

Interventions

Drug: CRB-913
Drug: Placebo

Primary outcomes

what the primary-completion date above is the date OF

Part 1: To evaluate the PK of a single dose of CRB-913 - Cmax

measured 0 to 48 hours

Part 1: To evaluate the PK of a single dose of CRB-913 - Tmax

measured 0 to 48 hours

Part 1: To evaluate the PK of a single dose of CRB-913 - T1/2

measured 0 to 48 hours

Part 2: To evaluate the safety of CRB-913 - TEAE

measured Day 1 to 28 days post final dose

Part 2: To evaluate the safety of CRB-913 - AESI

measured Day 1 to 28 days post final dose

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