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Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction - Coronary Computed Tomography Angiography Trial

← catalyst calendar

NCT07293260 · readout in 665 d

Sponsored by Amgen (industry) · AMGN — their whole pipeline →.

Phase
Phase 3
Status
Recruiting
Study type
Interventional
Design
Randomized · Double · Treatment
Enrollment
406estimated
Sites
40
Countries
Australia, Canada, China +8

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-03-23actualWhen the study began enrolling
Primary completion2028-06-15estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2028-06-15estimatedThe whole study's end, after follow-up
First posted2025-12-19actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-04-16actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Cardiovascular Disease

Interventions

  • Drug: Olpasiran — also filed as AMG 890
  • Drug: Placebo

Primary outcome

what the primary-completion date above is the date OF
Change in NCP Volume from Baseline to Week 72
measured Baseline to Week 72

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