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A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

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NCT07284849 · readout in 863 d

Sponsored by Incyte Corporation (industry) · INCY — their whole pipeline →.

Phase
Phase 3
Status
Recruiting
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
700estimated
Sites
254
Countries
Argentina, Australia, Austria +18

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-03-05actualWhen the study began enrolling
Primary completion2028-12-29estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2029-09-28estimatedThe whole study's end, after follow-up
First posted2025-12-16actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-08-06actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • CRC (Colorectal Cancer)

Interventions

  • Drug: INCA33890
  • Drug: Placebo
  • Drug: Bevacizumab
  • Drug: FOLFOX

Primary outcome

what the primary-completion date above is the date OF
Progression-Free Survival (PFS)
measured Up to 3 years

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