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Efficacy, Safety, Tolerability, and Biomarker Effects of GT-02287 in Early Parkinson's Disease

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NCT07280299 · readout in 681 d

Sponsored by Gain Therapeutics, Inc. (industry) · GANX — their whole pipeline →.

Phase
Phase 2
Status
Not yet recruiting
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
111estimated

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-05-30estimatedWhen the study began enrolling
Primary completion2028-06-30estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2028-06-30estimatedThe whole study's end, after follow-up
First posted2025-12-12actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2025-12-12actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Parkinson Disease

Interventions

  • Drug: Low Dose GT-02287 — also filed as GT-02287 400 or 600 mg/day
  • Drug: High Dose GT-02287 — also filed as GT-02287 800 or 1000 mg/day
  • Drug: Placebo — also filed as Magnesium aluminometasilicate (MAS)

Primary outcome

what the primary-completion date above is the date OF
Change from Baseline to Week 48 in the sum of the Movement Disorder Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Part II score and Part III score [Efficacy]
measured From baseline to Week 48

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