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A Study to Learn How Effective is PCV20 to Help Stop Adults Who Have a Higher Chance of Getting Pneumonia

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NCT07251465

Sponsored by Pfizer (industry) · PFE — their whole pipeline →. With Kaiser Permanente.

Phase
Status
Active, not recruiting
Study type
Observational
Enrollment
846,279actual
Sites
1
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-01-21actualWhen the study began enrolling
Primary completion2026-07-31estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2026-07-31estimatedThe whole study's end, after follow-up
First posted2025-11-26actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-06-22actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Pneumonia

Intervention

  • Biological: Receipt of PCV20

Primary outcome

what the primary-completion date above is the date OF
PCV20 vaccine effectiveness (VE) against all-cause pneumonia (ACP) calculated as (1- adjusted hazard ratio [aHR]) × 100% among adults aged ≥18-64 years with medical conditions and behavioral risk factors and among adults ≥65 years old, combined
measured 3 years

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