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A Study of LY4584180 in Adult Participants With Previously Treated Blood Cancers

← catalyst calendar

NCT07226843 · readout ≤ 254 d

Sponsored by Eli Lilly and Company (industry) · LLY — their whole pipeline →.

Phase
Phase 1
Status
Recruiting
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
460estimated
Sites
46
Countries
France, Germany, Italy +5

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-04-17actualWhen the study began enrolling
Primary completionApr 2027estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completionFeb 2030estimatedThe whole study's end, after follow-up
First posted2025-11-12actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-08-06actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Lymphoma, Non-Hodgkin's
  • Lymphoma, Diffuse Large B-Cell
  • Follicular Lymphoma

Interventions

  • Drug: LY4584180
  • Drug: Rituximab

Primary outcomes

what the primary-completion date above is the date OF
Number of Dose-Limiting Toxicities (DLTs) and DLT-Equivalent Toxicities
measured Baseline up to Day 28
Number of Participants with One or More Serious Adverse Events (SAEs) Considered by the Investigator to be Related to Study Drug Administration
measured Baseline up to 3 Years
To Evaluate the Preliminary Antitumor Activity of LY4584180: Objective Response Rate (ORR)
measured Baseline up to 3 Years

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