A Study of BG-75098 Alone and in Combination With Other Agents in Adults With Advanced Solid Tumors
← catalyst calendarNCT07226349 · readout in 805 d
Sponsored by BeOne Medicines (industry) · ONC — their whole pipeline →.
Phase
Phase 1
Status
Recruiting
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
105estimated
Sites
22
Countries
Australia, China, Denmark +1
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2025-12-11 | actual | When the study began enrolling |
| Primary completion | 2028-11-01 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2028-11-01 | estimated | The whole study's end, after follow-up |
| First posted | 2025-11-10 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-08-19 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Advanced Solid Tumor
Interventions
- Drug: BG-75098
- Drug: BGB-43395
- Drug: Fulvestrant
Primary outcomes
what the primary-completion date above is the date OFPhase 1a: Number of Participants with Adverse Events (AEs)
measured From first dose to 30 days after last dose, up to approximately 12 months
Phase 1a: Maximum Tolerated Dose (MTD) or Maximum Administered Dose (MAD) of BG-75098
measured Up to approximately 2 years
Phase 1a: Recommended Dose(s) for Expansion (RDFE[s]) of BG-75098 as Monotherapy and in Combination with BGB-43395 and Fulvestrant
measured Up to approximately 2 years
Phase 1b: Objective Response Rate (ORR) as Assessed by the Investigator
measured Up to approximately 2 years
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