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An Open-label Study of AZD0120 in Adults With Multiple Sclerosis

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NCT07224373 · readout in 846 d

Sponsored by AstraZeneca (industry) · AZN — their whole pipeline →.

Phase
Phase 1
Status
Recruiting
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
24estimated
Sites
19
Countries
Australia, Canada, Germany +2

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2025-12-09actualWhen the study began enrolling
Primary completion2028-12-12estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2028-12-12estimatedThe whole study's end, after follow-up
First posted2025-11-04actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-07-27actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Multiple Sclerosis

Interventions

  • Biological: AZD0120 - Regimen 1
  • Biological: AZD0120 - Regimen 2

Primary outcomes

what the primary-completion date above is the date OF
Evaluate the safety, and tolerability of AZD0120 in participants with MS (disease cohort 1: RMS; disease cohort 2: PMS)
measured Day 1 to day 29, and over 104 weeks
Evaluate the safety, and tolerability of AZD0120 in participants with MS (disease cohort 1: RMS; disease cohort 2: PMS)
measured Day 1 to day 29, and over 104 weeks
Evaluate the safety, and tolerability of AZD0120 in participants with MS (disease cohort 1: RMS; disease cohort 2: PMS)
measured Day 1 to day 29, and over 104 weeks
Evaluate the safety, and tolerability of AZD0120 in participants with MS (disease cohort 1: RMS; disease cohort 2: PMS)
measured Day 1 to day 29, and over 104 weeks

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