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Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

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NCT07214779 · readout in 819 d

Sponsored by Incyte Corporation (industry) · INCY — their whole pipeline →. With ENGOT Foundation, GOG Foundation.

Phase
Phase 3
Status
Recruiting
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
466estimated
Sites
181
Countries
Australia, Belgium, Canada +13

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2025-12-09actualWhen the study began enrolling
Primary completion2028-11-15estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2029-05-14estimatedThe whole study's end, after follow-up
First posted2025-10-09actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-08-06actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Ovarian Cancer

Interventions

  • Drug: INCB123667
  • Drug: Investigator's choice of chemotherapy — also filed as paclitaxel, pegylated liposomal doxorubicin (PLD), gemcitabine, topotecan

Primary outcomes

what the primary-completion date above is the date OF
Progression-Free Survival (PFS) by BICR
measured Up to 2 years
Overall Survival (OS)
measured Up to 2 years

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