Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer
← catalyst calendarNCT07214532 · readout in 4,106 d
Sponsored by Natera, Inc. (industry) · NTRA — their whole pipeline →.
Phase
Not applicable
Status
Recruiting
Study type
Interventional
Design
Na · None · Treatment
Enrollment
725estimated
Sites
48
Country
United States
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2026-05-08 | actual | When the study began enrolling |
| Primary completion | 2037-11-15 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2037-12-30 | estimated | The whole study's end, after follow-up |
| First posted | 2025-10-09 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-08-13 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Conditions
- Breast Neoplasms
- Carcinoma, Ductal, Breast
- Receptors, Estrogen (for ER-positive Requirement)
Intervention
- Device: ctDNA-Guided Treatment Strategy
Primary outcome
what the primary-completion date above is the date OFInvasive Disease-Free Survival
measured From the date of surgery up to 9 years
Publications
- PMID 37438589 — cited as background
- PMID 39294027 — cited as background
- PMID 37146605 — cited as background
- PMID 39216186 — cited as background
- PMID 39241962 — cited as background
- PMID 33630658 — cited as background
- PMID 37888087 — cited as background
- PMID 35213669 — cited as background
- PMID 35626173 — cited as background
- PMID 39817679 — cited as background
Linked on the registry record. A “linked by the registry” entry is NLM's own automated PubMed match, not a claim by the sponsor that the paper reports this study.
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