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A Study to Investigate the Pharmacokinetics and Safety of Subcutaneous Rilvegostomig in Adult Participants With Advanced Solid Tumors Previously Treated With Standard of Care Therapy

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NCT07161414 · readout in 333 d

Sponsored by AstraZeneca (industry) · AZN — their whole pipeline →. With Parexel.

Phase
Phase 1
Status
Recruiting
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
40estimated
Sites
11
Countries
South Korea, Spain, United Kingdom +1

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2025-11-25actualWhen the study began enrolling
Primary completion2027-07-19estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2029-07-24estimatedThe whole study's end, after follow-up
First posted2025-09-08actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-08-10actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Advanced Solid Tumors

Interventions

  • Drug: IV Rilvegostomig — also filed as AZD2936
  • Drug: Recombinant Human Hyaluronidase (rHu)
  • Drug: SC Rilvegostomig — also filed as AZD2936
  • Drug: SC rilvegostomig + rHu

Primary outcome

what the primary-completion date above is the date OF
Area under the Concentration-time Curve During One Dosing Interval (AUCtau)
measured From Day 1 up to end of Cycle 2 in Part 1 and end of Cycle 1 in Part 2 (each cycle will be of 3 weeks)

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