A Long-Term Study of Bivamelagon in Participants With Hypothalamic Obesity (HO)
← catalyst calendarNCT07156578 · readout in 605 d
Sponsored by Rhythm Pharmaceuticals, Inc. (industry) · RYTM — their whole pipeline →.
Phase
Phase 2
Status
Enrolling by invitation
Study type
Interventional
Design
Na · None · Treatment
Enrollment
25estimated
Sites
9
Countries
United Kingdom, United States
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2025-11-10 | actual | When the study began enrolling |
| Primary completion | 2028-04-15 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2028-04-15 | estimated | The whole study's end, after follow-up |
| First posted | 2025-09-05 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-02-10 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Hypothalamic Obesity
Intervention
- Drug: Bivamelagon
Primary outcome
what the primary-completion date above is the date OFSafety and tolerability of bivamelagon as assessed by the number and frequency of AEs
measured Baseline to up to 2 years
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