OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
← catalyst calendarNCT07136012 · readout in 1,888 d
Sponsored by Amgen (industry) · AMGN — their whole pipeline →.
Phase
Phase 3
Status
Recruiting
Study type
Interventional
Design
Randomized · Double · Treatment
Enrollment
11,000estimated
Sites
252
Countries
Australia, Canada, United States
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2025-08-22 | actual | When the study began enrolling |
| Primary completion | 2031-10-20 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2031-10-20 | estimated | The whole study's end, after follow-up |
| First posted | 2025-08-22 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-08-13 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Cardiovascular Disease
Interventions
- Drug: Olpasiran — also filed as AMG 890
- Drug: Placebo
Primary outcome
what the primary-completion date above is the date OFTime to CHD Death, Myocardial Infarction, or Urgent Coronary Revascularization, Whichever Occurs First
measured Up to approximately 6.2 years
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