Study of GS-5319 Given Alone or in Combination in Adults With Solid Tumors
← catalyst calendarNCT07128303 · readout ≤ 651 d
Sponsored by Gilead Sciences (industry) · GILD — their whole pipeline →.
Phase
Phase 1
Status
Recruiting
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
476estimated
Sites
11
Countries
South Korea, Spain, United States
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2025-08-28 | actual | When the study began enrolling |
| Primary completion | May 2028 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | May 2028 | estimated | The whole study's end, after follow-up |
| First posted | 2025-08-17 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-08-19 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Advanced Solid Tumor
Interventions
- Drug: GS-5319
- Drug: Carboplatin
- Drug: Pemetrexed
- Drug: Pembrolizumab
Primary outcomes
what the primary-completion date above is the date OFPercentage of Participants With Adverse Events (AEs) and Serous Adverse Events (SAEs)
measured Up to 2 years
Percentage of Participants Experiencing Laboratory Abnormalities
measured Up to 2 years
Percentage of Participants Experiencing any Dose-limiting Toxicities (DLTs) in Dose-escalation Cohorts
measured Up to 21 days
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