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DESTINY-PANTUMOUR04

← catalyst calendar

NCT07124000 · readout in 589 d

Sponsored by AstraZeneca (industry) · AZN — their whole pipeline →.

Phase
Status
Recruiting
Study type
Observational
Enrollment
100estimated
Sites
18
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2025-09-18actualWhen the study began enrolling
Primary completion2028-03-30estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2028-03-30estimatedThe whole study's end, after follow-up
First posted2025-08-15actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-07-22actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Adenocarcinoma (NOS)
  • Anal Cancer
  • Bladder Cancer
  • Cervical Cancer
  • Endometrial Cancer
  • Esophageal Cancer
  • Gall Bladder Cancer
  • Gastrointestinal Stromal Tumour
  • Head and Neck Cancer
  • Liver Cancer
  • Melanoma
  • Mouth Cancer
  • Nasopharangeal Cancer
  • Neuroendocrine, Gastrointestinal Cancer
  • Ovarian Cancer
  • Pancreatic Cancer
  • Prostate Cancer
  • Renal Cell Carcinoma
  • Salivary Gland Cancer
  • Sarcoma
  • Small Cell Lung Cancer
  • Testicular Cancer
  • Throat Cancer
  • Thyroid Cancer
  • Urethral Cancer
  • Vaginal Cancer
  • Vulvar Cancer

Intervention

  • Drug: Trastuzumab deruxtecan — also filed as Enhertu

Primary outcomes

what the primary-completion date above is the date OF
Real world response rate (rwRR)
measured Through study completion, up to 2.5 years after enrolment
Real world duration of response (rwDoR)
measured Through study completion, up to 2.5 years after enrolment

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