A First-in-Human Phase 1 Single-Ascending Dose Study of ABCL575 in Healthy Participants
← catalyst calendarNCT07108894 · readout ≤ 254 d
Sponsored by AbCellera Biologics Inc. (industry) · ABCL — their whole pipeline →.
Phase
Phase 1
Status
Active, not recruiting
Study type
Interventional
Design
Randomized · Triple · Treatment
Enrollment
40estimated
Sites
1
Country
Canada
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2025-07-25 | actual | When the study began enrolling |
| Primary completion | Apr 2027 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | Apr 2027 | estimated | The whole study's end, after follow-up |
| First posted | 2025-08-07 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-06-16 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Healthy Volunteers
Interventions
- Biological: ABCL575
- Biological: Placebo (Normal Saline 0.9%)
Primary outcomes
what the primary-completion date above is the date OFIncidence, frequency, and severity of adverse events (AEs)
measured Day 0 to day 337
Changes from baseline in laboratory parameters including general biochemistry, lipid profile, coagulation, hematology, and urinalysis
measured Day 0 to day 337
Changes from baseline in physical examination
measured Day 0 to day 337
Changes from baseline in vital signs
measured Day 0 to day 337
Changes from baseline in 12-lead safety ECGs
measured Day 0 to day 337
Incidence and severity of injection site reactions
measured Day 0 to day 337
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