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A Phase III Control Study of the Safety and Immunogenicity of vYF in Pediatric Population

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NCT07103148

Sponsored by Sanofi (industry) · SNY — their whole pipeline →.

Phase
Phase 3
Status
Recruiting
Study type
Interventional
Design
Randomized · Quadruple · Prevention
Enrollment
2,440estimated
Sites
13
Countries
Honduras, Mexico, Panama

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2025-07-11actualWhen the study began enrolling
Primary completion2026-08-08estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2030-03-04estimatedThe whole study's end, after follow-up
First posted2025-08-05actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-05-06actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Yellow Fever Immunization

Interventions

  • Biological: Yellow fever vaccine (live) — also filed as vYF vaccine
  • Biological: Yellow fever vaccine (live) — also filed as Stamaril vaccine
  • Biological: Yellow fever vaccine (live) — also filed as YF-VAX vaccine
  • Biological: Measles, combinations with mumps and rubella, live attenuated — also filed as MMR II vaccine

Primary outcomes

what the primary-completion date above is the date OF
Percentage of participants with seroconversion to YF virus after 1 dose of vYF compared to seroconversion after 1 dose of the Stamaril in YF-naive participants (9-24 months)
measured At Day 29, 28 days post-vaccination (on Day 01) with vYF or Stamaril
Percentage of participants with seroconversion to YF virus after 1 dose of vYF compared to seroconversion after 1 dose of the YF-VAX in YF-naive participants (9-24 months)
measured At Day 29, 28 days post-vaccination (on Day 01) with vYF or YF-VAX
Percentage of participants with seroconversion to YF virus after 1 dose of vYF compared to seroconversion after 1 dose of the Stamaril in YF-naive participants (2-5 years)
measured At Day 29, 28 days post-vaccination (on Day 01) with vYF or Stamaril
Percentage of participants with seroconversion to YF virus after 1 dose of vYF compared to seroconversion after 1 dose of the YF-VAX in YF-naive participants (2-5 years)
measured At Day 29, 28 days post-vaccination (on Day 01) with vYF or YF-VAX

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