A Phase 1 Study of Budoprutug (TNT119) Subcutaneous and Intravenous Injections in Normal Healthy Volunteers
← catalyst calendarSponsored by Climb Bio, Inc. (industry) · CLYM — their whole pipeline →.
Phase
Early Phase 1
Status
Completed
Study type
Interventional
Design
Randomized · Double · Basic science
Enrollment
30actual
Sites
1
Country
Australia
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2025-08-11 | actual | When the study began enrolling |
| Primary completion | 2026-04-07 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2026-04-07 | actual | The whole study's end, after follow-up |
| First posted | 2025-07-29 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-07-30 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Healthy Volunteers
Interventions
- Drug: Budoprutug — also filed as TNT119
- Drug: Placebo
Primary outcomes
what the primary-completion date above is the date OFSafety and Tolerability of Single Ascending Doses of budoprutug in Healthy Participants
measured Day 57
Incidence of infusion-related reactions (IRRs) for IV administration
measured Day 57
Incidence of injection site reactions (ISRs) for SC administration
measured Day 57
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