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REGN7508 Versus Apixaban and Enoxaparin for Thromboprophylaxis After Total Knee Arthroplasty in Adults

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NCT07015905 · readout in 185 d

Sponsored by Regeneron Pharmaceuticals (industry) · REGN — their whole pipeline →.

Phase
Phase 3
Status
Recruiting
Study type
Interventional
Design
Randomized · Double · Treatment
Enrollment
2,000estimated
Sites
46
Countries
Bulgaria, Hungary, Japan +5

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2025-06-25actualWhen the study began enrolling
Primary completion2027-02-20estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2027-05-12estimatedThe whole study's end, after follow-up
First posted2025-06-11actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-07-13actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Venous Thromboembolism (VTE)

Interventions

  • Drug: REGN7508 — also filed as cenvacibart
  • Drug: Apixaban
  • Drug: Enoxaparin — also filed as Inhixa
  • Drug: Placebo

Primary outcome

what the primary-completion date above is the date OF
Incidence of the composite endpoint of asymptomatic or symptomatic Venous Thromboembolism (VTE) [including VTE-related death]
measured Through day 12 visit, approximately 14 days

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