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A Study in Healthy Participants to Investigate Relative Bioavailability of AZD5004 in Three Solid Oral Formulations

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NCT06996886

Sponsored by AstraZeneca (industry) · AZN — their whole pipeline →. With Parexel.

Phase
Phase 1
Status
Completed
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
16actual
Sites
1
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2025-05-22actualWhen the study began enrolling
Primary completion2025-07-15actualThe date the last participant is measured for the primary outcome — the readout window
Study completion2025-07-25actualThe whole study's end, after follow-up
First posted2025-05-30actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2025-07-31actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Healthy Participants

Intervention

  • Drug: AZD5004

Primary outcomes

what the primary-completion date above is the date OF
Area under concentration-time curve from time 0 to infinity (AUCinf)
measured Day 1-6, Day 8-13, Day 15-20 and Day 22-27
Area under concentration-curve from time 0 to the last quantifiable concentration (AUClast)
measured Day 1-6, Day 8-13, Day 15-20 and Day 22-27
Maximum observed drug concentration (Cmax)
measured Day 1-6, Day 8-13, Day 15-20 and Day 22-27
Time to reach maximum observed concentration (tmax)
measured Day 1-6, Day 8-13, Day 15-20 and Day 22-27
Half-life (t½)
measured Day 1-6, Day 8-13, Day 15-20 and Day 22-27
Apparent total body clearance (CL/F)
measured Day 1-6, Day 8-13, Day 15-20 and Day 22-27

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