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A Platform Study in Non-Small Cell Lung Cancer (NSCLC)

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NCT06996782 · readout in 919 d

Sponsored by AstraZeneca (industry) · AZN — their whole pipeline →.

Phase
Phase 1/2
Status
Recruiting
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
152estimated
Sites
103
Countries
Belgium, Brazil, China +17

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2025-11-24actualWhen the study began enrolling
Primary completion2029-02-23estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2029-02-23estimatedThe whole study's end, after follow-up
First posted2025-05-30actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-07-21actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Advanced or Metastatic Non-small Cell Lung Cancer

Interventions

  • Drug: Rilvegostomig — also filed as AZD2936
  • Drug: Cisplatin
  • Drug: Carboplatin
  • Drug: Pemetrexed
  • Drug: Paclitaxel
  • Drug: Nab-paclitaxel
  • Drug: Ramucirumab

Primary outcomes

what the primary-completion date above is the date OF
Part A and Part B: Number of participants with adverse events (AEs) and serious adverse events (SAEs)
measured Approximately 46 months
Part A: Number of partcipants with dose limiting toxicity (DLT)
measured Approximately 46 months
Part B: Objective response (OR)
measured Approximately 46 months

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