A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma
← catalyst calendarNCT06977581 · readout in 201 d
Sponsored by Pfizer (industry) · PFE — their whole pipeline →.
Phase
Phase 2
Status
Recruiting
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
252estimated
Sites
132
Countries
Argentina, Belgium, Bulgaria +12
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2025-05-20 | actual | When the study began enrolling |
| Primary completion | 2027-03-08 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2027-05-31 | estimated | The whole study's end, after follow-up |
| First posted | 2025-05-18 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-05-04 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Asthma
Interventions
- Drug: PF-07275315
- Other: Placebo
Primary outcomes
what the primary-completion date above is the date OFChange from baseline in pre-bronchodilator Forced Expiratory Volume in 1 Second (FEV1) at Week 12
measured Week 12
Treatment-Emergent Adverse Events (AEs), Serious AEs (SAEs), and AEs/SAEs leading to treatment discontinuation
measured Baseline through Week 24
Clinically significant, treatment-related laboratory abnormalities
measured Baseline through Week 24
Clinically significant, treatment-related abnormalities in vital signs
measured Baseline through Week 24
Clinically significant, treatment-related electrocardiogram (ECG) abnormalities
measured Baseline through Week 24
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