A Study to Investigate the Relative Bioavailability of 2 Different Formulations of AZD4144, the Effect of Food and Omeprazole on the Pharmacokinetics of AZD4144 in Healthy Participants
← catalyst calendarSponsored by AstraZeneca (industry) · AZN — their whole pipeline →. With Parexel.
Phase
Phase 1
Status
Completed
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
32actual
Sites
1
Country
United Kingdom
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2025-04-23 | actual | When the study began enrolling |
| Primary completion | 2025-06-27 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2025-06-27 | actual | The whole study's end, after follow-up |
| First posted | 2025-04-28 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2025-07-23 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Healthy Participants
Interventions
- Drug: AZD4144
- Drug: Omeprazole
Primary outcomes
what the primary-completion date above is the date OFArea under concentration-time curve from time 0 to infinity (AUCinf) of AZD4144
measured Days 1-4, Days 8-11 and Days 15-18
Area under concentration-curve from time 0 to the last quantifiable concentration (AUClast) of AZD4144
measured Days 1-4, Days 8-11 and Days 15-18
Maximum observed drug concentration (Cmax) of AZD4144
measured Days 1-4, Days 8-11 and Days 15-18
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