A Study of MET233 in Combination With MET097 in Individuals With Obesity or Overweight With or Without Diabetes
← catalyst calendarNCT06924320 · readout in 27 d
Sponsored by Pfizer (industry) · PFE — their whole pipeline →.
Phase
Phase 1/2
Status
Recruiting
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
381estimated
Sites
1
Country
United States
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2025-03-06 | actual | When the study began enrolling |
| Primary completion | 2026-09-15 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2026-09-15 | estimated | The whole study's end, after follow-up |
| First posted | 2025-04-11 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-06-01 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Obesity and Obesity-related Medical Conditions
Interventions
- Drug: MET233 and MET097
- Other: Placebo
- Drug: MET097
Primary outcome
what the primary-completion date above is the date OFOccurrence of treatment-emergent adverse events (TEAEs)
measured Part A (Baseline, Day 85), Part B (Baseline, Day 155), Part C (Baseline, Day 155), Part D (Baseline, Day 218), Part E (Baseline, Day 246), Part G (Baseline, Day 274)
Publications
- PMID 41747885 — linked by the registry
Linked on the registry record. A “linked by the registry” entry is NLM's own automated PubMed match, not a claim by the sponsor that the paper reports this study.
Permalink · PFE's whole pipeline · Catalyst calendar · Every registered study · What changed