Drug-Drug Interaction Study of Casdatifan in Healthy Adult Participants (ARC-29)
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Phase
Phase 1
Status
Completed
Study type
Interventional
Design
Na · None · Basic science
Enrollment
14actual
Sites
1
Country
United States
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2025-05-02 | actual | When the study began enrolling |
| Primary completion | 2025-10-18 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2025-10-18 | actual | The whole study's end, after follow-up |
| First posted | 2025-04-09 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2025-11-13 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Healthy Participants
Interventions
- Drug: Casdatifan
- Drug: Itraconazole
- Drug: Phenytoin
Primary outcomes
what the primary-completion date above is the date OFArea Under the Plasma Drug Concentration-Time Curve (AUC) for casdatifan
measured Up to 168 hours post dose for Period 1; up to 216 hours post dose for Period 2; and up to 120 hours post dose for Period 3
Maximum Concentration (Cmax) in Plasma for casdatifan
measured Up to 168 hours post dose for Period 1; up to 216 hours post dose for Period 2; and up to 120 hours post dose for Period 3
Time to Maximum Concentration (Tmax) in Plasma for casdatifan
measured Up to 168 hours post dose for Period 1; up to 216 hours post dose for Period 2; and up to 120 hours post dose for Period 3
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