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A Study to Learn if Study Medicines Called Cyclosporine and Clarithromycin Affect How the Body Processes the Other Study Medicine Called PF-07328948 in Healthy Adults

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NCT06837259

Sponsored by Pfizer (industry) · PFE — their whole pipeline →.

Phase
Phase 1
Status
Completed
Study type
Interventional
Design
Randomized · None · Basic science
Enrollment
26actual
Sites
1
Country
Belgium

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2025-03-19actualWhen the study began enrolling
Primary completion2025-06-11actualThe date the last participant is measured for the primary outcome — the readout window
Study completion2025-06-11actualThe whole study's end, after follow-up
First posted2025-02-20actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-02-02actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Healthy Adults

Interventions

  • Drug: PF-07328948
  • Drug: cyclosporine
  • Drug: clarithromycin

Primary outcomes

what the primary-completion date above is the date OF
Maximum Observed Plasma Concentration (Cmax) of PF-07328948
measured Hour 0, 1, 2, 3, 4, 6, 8, 10, 12, 24, 36, 48, 72 post-dose
Area Under the Curve From Time Zero to Extrapolated Infinite Time (AUCinf) of PF-07328948
measured Hour 0, 1, 2, 3, 4, 6, 8, 10, 12, 24, 36, 48, 72 post-dose
Area under the plasma concentration-time curve from time 0 to the time of the last quantifiable concentration (AUClast) of PF-07328948
measured Hour 0, 1, 2, 3, 4, 6, 8, 10, 12, 24, 36, 48, 72 post-dose

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