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ARD-101 for Treatment of PWS: The Hunger Elimination or Reduction Objective Trial

← catalyst calendar

NCT06828861

Sponsored by Aardvark Therapeutics, Inc. (industry) · AARD — their whole pipeline →.

Phase
Phase 3
Status
Terminated
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
68actual
Sites
31
Countries
Australia, Canada, South Korea +2

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Why the sponsor stopped it

Due to operational and regulatory considerations.

As filed on the registry record, in the sponsor's own words.

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2024-12-20actualWhen the study began enrolling
Primary completion2026-05-07actualThe date the last participant is measured for the primary outcome — the readout window
Study completion2026-05-07actualThe whole study's end, after follow-up
First posted2025-02-17actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-06-30actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Hyperphagia
  • Prader-Willi Syndrome

Interventions

  • Drug: Placebo
  • Drug: ARD-101

Primary outcome

what the primary-completion date above is the date OF
Change in Hyperphagia Questionnaire for Clinical Trials (HQ-CT) Score
measured Baseline to Week 12

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