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Treatment of Type 1 Diabetes With Anti-OX40L Bispecific With Anti-TNF Activity In a Single Nanobody® Molecule

← catalyst calendar

NCT06812988 · readout in 253 d

Sponsored by Sanofi (industry) · SNY — their whole pipeline →.

Phase
Phase 2
Status
Active, not recruiting
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
84estimated
Sites
24
Countries
Argentina, Australia, Brazil +5

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2025-02-28actualWhen the study began enrolling
Primary completion2027-04-29estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2027-04-29estimatedThe whole study's end, after follow-up
First posted2025-02-06actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-03-13actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Type 1 Diabetes Mellitus

Interventions

  • Drug: Brivekimig
  • Drug: Placebo

Primary outcome

what the primary-completion date above is the date OF
Change from baseline to Week 26 in mean 2-hour mixed meal tolerance test (MMTT) stimulated C-peptide concentration
measured From Baseline to Week 26

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