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Inaxaplin in Participants With Proteinuric APOL1 Mediated Kidney Disease With or Without Comorbidities

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NCT06794996 · readout in 133 d

Sponsored by Vertex Pharmaceuticals Incorporated (industry) · VRTX — their whole pipeline →.

Phase
Phase 2
Status
Active, not recruiting
Study type
Interventional
Design
Na · None · Treatment
Enrollment
42actual
Sites
35
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2025-02-04actualWhen the study began enrolling
Primary completion2026-12-30estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2026-12-30estimatedThe whole study's end, after follow-up
First posted2025-01-27actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-05-05actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Proteinuric Kidney Disease

Intervention

  • Drug: Inaxaplin — also filed as IXP, VX-147

Primary outcome

what the primary-completion date above is the date OF
Percent Change in Urine Albumin-Creatinine Ratio (UACR)
measured Baseline and At Week 13

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