A Study to Evaluate the Safety, Tolerability, PK, and PD Effects of AZD2389 in Participants With Liver Fibrosis and Compensated Cirrhosis.
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Phase
Phase 2
Status
Completed
Study type
Interventional
Design
Randomized · Double · Treatment
Enrollment
40actual
Sites
9
Countries
Puerto Rico, United Kingdom, United States
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2024-12-06 | actual | When the study began enrolling |
| Primary completion | 2025-07-28 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2025-07-28 | actual | The whole study's end, after follow-up |
| First posted | 2024-12-27 | actual | When this record first appeared on the registry |
| Results posted | 2026-07-06 | actual | When the sponsor posted results to the registry |
| Record updated | 2026-07-06 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Conditions
- Liver Fibrosis
- Hepatic Cirrhosis
Intervention
- Drug: AZD2389
Primary outcomes
what the primary-completion date above is the date OFNotable Trends in Laboratory Assessments (Haematology, Coagulation, Clinical Chemistry, Fibrinolysis, and Urinalysis)
measured From screening up to and including Day 35
Clinically Relevant Trends in Vital Signs (Blood Pressure, Pulse Rate, Oxygen Saturation, Body Temperature, and Respiration Rate), and 12-lead Electrocardiogram (ECG)
measured From Screening up to and including Day 35
Posted documents
hosted by the registry — we link, never re-serveStudy Protocolposted 2025-04-17 · 3.8 MB · Prot_000.pdf
Statistical Analysis Planposted 2025-09-10 · 2.0 MB · SAP_001.pdf
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