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A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)

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NCT06749457 · readout in 226 d

Sponsored by AstraZeneca (industry) · AZN — their whole pipeline →. With Parexel.

Phase
Phase 1/2
Status
Recruiting
Study type
Interventional
Design
Randomized · Quadruple · Prevention
Enrollment
231estimated
Sites
44
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2024-12-30actualWhen the study began enrolling
Primary completion2027-04-02estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2028-01-07estimatedThe whole study's end, after follow-up
First posted2024-12-27actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-08-14actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Staphylococcus Aureus

Interventions

  • Drug: AZD7760
  • Other: Placebo

Primary outcomes

what the primary-completion date above is the date OF
Phase I: Occurence of adverse events (AEs)
measured Day 1 to Day 181
Phase I: Occurence of medically-attended adverse events (MAAEs), serious adverse events (SAEs), and adverse events of special interest (AESIs)
measured Day 1 to Day 361
Phase IIa: Occurrence of AEs, MAAEs, SAEs, and AESIs
measured Day 1 to Day 181

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