PET Study of PIPE-791 in Healthy Volunteers and Volunteers With PrMS and IPF
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Phase
Phase 1
Status
Completed
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
16actual
Sites
1
Country
United Kingdom
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2024-12-09 | actual | When the study began enrolling |
| Primary completion | 2025-06-04 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2025-06-12 | actual | The whole study's end, after follow-up |
| First posted | 2024-11-12 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2025-08-06 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Conditions
- Idiopathic Pulmonary Fibrosis (IPF)
- Idiopathic Pulmonary Fibrosis
- Multiple Sclerosis
- Multiple Sclerosis, MS
- Multiple Sclerosis, Primary Progressive
- Multiple Sclerosis, Progressive
- Multiple Sclerosis, Secondary Progressive
- Healthy
- Healthy Volunteers
Intervention
- Drug: PIPE-791
Primary outcomes
what the primary-completion date above is the date OFLPA1 occupancy as determined by regional total volume of distribution (VT) at each brain scan.
measured Baseline to up to 28 days post-dose
LPA1 occupancy as determined by regional total volume of distribution (VT) at each lung scan.
measured Baseline to up to 28 days post-dose
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