A Study to Evaluate ALN-6400 in Healthy Volunteers and Patients With Hereditary Hemorrhagic Telangiectasia (HHT)
← catalyst calendarNCT06659640 · readout in 504 d
Sponsored by Alnylam Pharmaceuticals (industry) · ALNY — their whole pipeline →.
Phase
Phase 1/2
Status
Active, not recruiting
Study type
Interventional
Design
Randomized · Triple · Treatment
Enrollment
89actual
Sites
16
Countries
Australia, Canada, France +3
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2024-11-07 | actual | When the study began enrolling |
| Primary completion | 2028-01-05 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2028-06-22 | estimated | The whole study's end, after follow-up |
| First posted | 2024-10-26 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-08-12 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Hereditary Hemorrhagic Telangiectasia
Interventions
- Drug: ALN-6400
- Drug: Placebo
Primary outcomes
what the primary-completion date above is the date OFPart A: Frequency of Adverse Events
measured Up to Week 36
Part B: Frequency of Adverse Events
measured Up to Week 96
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