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First-in-Human Trial of DS-2243a in Participants With Advanced Solid Tumors

← catalyst calendar

NCT06644755 · readout in 834 d

Sponsored by Daiichi Sankyo (industry) · 4568.T — their whole pipeline →.

Phase
Phase 1
Status
Recruiting
Study type
Interventional
Design
Na · None · Treatment
Enrollment
150estimated
Sites
7
Countries
Belgium, France, Netherlands +2

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2024-11-14actualWhen the study began enrolling
Primary completion2028-11-30estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2028-11-30estimatedThe whole study's end, after follow-up
First posted2024-10-16actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2025-07-24actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Solid Tumors
  • Sarcoma

Intervention

  • Drug: DS-2243a

Primary outcomes

what the primary-completion date above is the date OF
Part 1: Number of participants with Dose-Limiting Toxicities at each dose level of DS-2243a
measured Up to 18 months
Part 2: Number of participants with Treatment-Emergent Adverse Events
measured Up to 3 years
Part 2: Objective Response Rate
measured From day of first dose up to 3 years

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