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A Study to Investigate Weight Management With Bimagrumab (LY3985863) and Tirzepatide (LY3298176), Alone or in Combination, in Adults With Obesity or Overweight

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NCT06643728

Sponsored by Eli Lilly and Company (industry) · LLY — their whole pipeline →.

Phase
Phase 2
Status
Active, not recruiting
Study type
Interventional
Design
Randomized · Double · Treatment
Enrollment
252actual
Sites
12
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2024-10-21actualWhen the study began enrolling
Primary completion2026-01-16actualThe date the last participant is measured for the primary outcome — the readout window
Study completionJan 2027estimatedThe whole study's end, after follow-up
First posted2024-10-16actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-05-26actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Obesity
  • Overweight

Interventions

  • Drug: Bimagrumab — also filed as LY3985863, BYM338, VER201
  • Drug: Tirzepatide — also filed as LY3298176
  • Drug: Bimagrumab Placebo
  • Drug: Tirzepatide Placebo

Primary outcome

what the primary-completion date above is the date OF
Percent Change from Baseline in Body Weight
measured Baseline, Week 24

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