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A Phase 3 Study in Moderate-to-Severe Plaque Psoriasis With Piclidenoson to Study Safety and Efficacy

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NCT06643260 · readout ≤ 498 d

Sponsored by Can-Fite BioPharma (industry) · CANF — their whole pipeline →.

Phase
Phase 3
Status
Not yet recruiting
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
705estimated

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
StartJun 2025estimatedWhen the study began enrolling
Primary completionDec 2027estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completionJun 2028estimatedThe whole study's end, after follow-up
First posted2024-10-16actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2025-04-29actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Plaque Psoriasis

Interventions

  • Drug: piclidenoson
  • Drug: Placebo

Primary outcomes

what the primary-completion date above is the date OF
Proportion of subjects who achieve a Psoriasis Area and Severity Index (PASI) score response of ≥75% (PASI 75)
measured 16 weeks
proportion of subjects who achieve a Static Physician's Global Assessment (sPGA) of 0 or 1 with at least a 2-point improvement from Baseline
measured 16 weeks
Proportion of subjects who experience adverse events
measured 52 weeks

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