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Phase 4 Paediatric Study to Evaluate Sonazoid Safety and Efficacy for Contrast-Enhanced Ultrasound Liver Imaging

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NCT06639828

Sponsored by GE Healthcare (industry) · GEHC — their whole pipeline →. With PPD Development, LP, Medidata Solutions.

Phase
Phase 4
Status
Recruiting
Study type
Interventional
Design
Na · None · Diagnostic
Enrollment
50estimated
Sites
6
Countries
Germany, Italy, United Kingdom

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2025-01-20actualWhen the study began enrolling
Primary completion2026-07-31estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2026-10-31estimatedThe whole study's end, after follow-up
First posted2024-10-15actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-03-04actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Focal Liver Lesions

Intervention

  • Diagnostic test: Contrast-Enhanced Ultrasound

Primary outcomes

what the primary-completion date above is the date OF
Accuracy of Sonazoid-enhanced ultrasound at imaging focal liver lesions during the vascular phase of imaging
measured Images to be captured during the studies CEUS examination [approximately 5 seconds prior to bolus injection, up to 4-minutes post injection for the vascular phase] and blinded image evaluations shall be executed remotely at a central lab
Sensitivity of Sonazoid-enhanced ultrasound at imaging focal liver lesions during the vascular phase of imaging
measured Images to be captured during the studies CEUS examination [approximately 5 seconds prior to bolus injection, up to 4-minutes post injection for the vascular phase] and blinded image evaluations shall be executed remotely at a central lab
Specificity of Sonazoid-enhanced ultrasound at imaging focal liver lesions during the vascular phase of imaging
measured Images to be captured during the studies CEUS examination [approximately 5 seconds prior to bolus injection, up to 4-minutes post injection for the vascular phase] and blinded image evaluations shall be executed remotely at a central lab

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