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Dose-Escalation of MNPR-101-PCTA-177Lu in Solid Tumors

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NCT06617169 · readout ≤ 134 d

Sponsored by Monopar Therapeutics (industry) · MNPR — their whole pipeline →.

Phase
Phase 1
Status
Recruiting
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
12estimated
Sites
1
Country
Australia

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2024-10-08actualWhen the study began enrolling
Primary completionDec 2026estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completionJan 2027estimatedThe whole study's end, after follow-up
First posted2024-09-27actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2025-05-21actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Solid Tumor, Adult
  • Bladder Cancer
  • Urothelial Carcinoma
  • Triple-negative Breast Cancer
  • Lung Cancer
  • Colorectal Cancer
  • Gastric Cancer
  • Ovarian Cancer
  • Pancreatic Cancer

Intervention

  • Drug: MNPR-101-PCTA-177Lu

Primary outcomes

what the primary-completion date above is the date OF
Identify the dose-limiting toxicities (DLTs) of fractionated MNPR-101-PCTA-177Lu dosing and their frequency
measured For 6 weeks after the first dose
Incidence of Treatment-Emergent Adverse Events [Safety and Tolerability] of fractionated MNPR-101-PCTA-177Lu dosing
measured From dosing to the End of Study at 24 weeks

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