A Study of mRNA-1010 Compared With a Licensed Influenza Vaccine in Adults ≥50 Years of Age
← catalyst calendarSponsored by ModernaTX, Inc. (industry) · MRNA — their whole pipeline →.
Phase
Phase 3
Status
Completed
Study type
Interventional
Design
Randomized · Triple · Prevention
Enrollment
40,817actual
Sites
301
Countries
Belgium, Bulgaria, Canada +8
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2024-09-16 | actual | When the study began enrolling |
| Primary completion | 2025-08-21 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2025-08-21 | actual | The whole study's end, after follow-up |
| First posted | 2024-09-19 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2025-09-10 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Seasonal Influenza
Interventions
- Biological: mRNA-1010
- Biological: Fluarix®
- Biological: Influsplit® Tetra
- Biological: Fluarix Tetra
- Biological: Alpharix® Tetra
Primary outcomes
what the primary-completion date above is the date OFNumber of Participants with Solicited Local and Systemic Adverse Reactions (ARs)
measured Day 1 to Day 7
Number of Participants with Unsolicited Adverse Events (AEs)
measured Day 1 to Day 28
Number of Participants with Medically Attended AEs (MAAEs), AEs Leading to Discontinuation, Serious Adverse Events (SAEs), or Adverse Events of Special Interest (AESI)
measured Day 1 to Day 181
Time to First Episode of RT-PCR Confirmed Protocol Defined ILI
measured Day 14 up to End of Season (up to approximately Day 181)
Publications
- PMID 42090792 — linked by the registry
Linked on the registry record. A “linked by the registry” entry is NLM's own automated PubMed match, not a claim by the sponsor that the paper reports this study.
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