A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease
← catalyst calendarNCT06585774 · readout in 405 d
Sponsored by Incyte Corporation (industry) · INCY — their whole pipeline →.
Phase
Phase 3
Status
Recruiting
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
240estimated
Sites
126
Countries
Australia, Austria, Canada +10
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2025-01-21 | actual | When the study began enrolling |
| Primary completion | 2027-09-28 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2030-03-31 | estimated | The whole study's end, after follow-up |
| First posted | 2024-09-19 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-08-06 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Chronic Graft-versus-host-disease
Interventions
- Drug: INCA034176 — also filed as Axatilimab
- Drug: Placebo
- Drug: Corticosteroids — also filed as prednisone, methylprednisolone, prednisolone
Primary outcome
what the primary-completion date above is the date OFEvent Free Survival (EFS)
measured Up to 3 years
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