A Study to Evaluate ALN-HTT02 in Adult Patients With Huntington's Disease
← catalyst calendarNCT06585449 · readout in 686 d
Sponsored by Alnylam Pharmaceuticals (industry) · ALNY — their whole pipeline →.
Phase
Phase 1
Status
Recruiting
Study type
Interventional
Design
Randomized · Triple · Treatment
Enrollment
66estimated
Sites
19
Countries
Canada, Germany, United Kingdom
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2024-10-14 | actual | When the study began enrolling |
| Primary completion | 2028-07-05 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2028-07-05 | estimated | The whole study's end, after follow-up |
| First posted | 2024-09-05 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-08-12 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Huntington's Disease
Interventions
- Drug: ALN-HTT02
- Drug: Placebo
Primary outcomes
what the primary-completion date above is the date OFFrequency of Adverse Events (AEs) in the Double-blind Part of the Study
measured Up to 12 months
Frequency of AEs in the Open-label Part of the Study
measured Up to 12 months
Frequency of AEs in the OLE Part of the Study
measured Up to 36 months
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