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Zopa Retreatment and Vector Shedding in Adults With RRP

← catalyst calendar

NCT06538480 · readout in 470 d

Sponsored by Precigen, Inc (industry) · PGEN — their whole pipeline →.

Phase
Phase 4
Status
Recruiting
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
30estimated
Sites
3
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2024-07-11actualWhen the study began enrolling
Primary completion2027-12-02estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2028-12-02estimatedThe whole study's end, after follow-up
First posted2024-08-05actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2025-12-15actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Recurrent Respiratory Papillomatosis
  • Papillomavirus Infection
  • Papillomaviridae

Intervention

  • Drug: Zopapogene imadenovec (Zopa)

Primary outcomes

what the primary-completion date above is the date OF
Cohort 1 Vector shedding
measured Up to 6 weeks following last administration, with additional collections if needed until two consecutive measurements at or below limit of detection
Cohort 2 Complete Response Rate
measured 12 months following last administration

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