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Extension Study to Evaluate the Long-Term Safety and Tolerability of MBX 2109 in Patients With Hypoparathyroidism

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NCT06531941 · readout in 281 d

Sponsored by MBX Biosciences (industry) · MBX — their whole pipeline →.

Phase
Phase 2
Status
Active, not recruiting
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
60actual
Sites
23
Countries
Argentina, Turkey (Türkiye), United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2024-10-31actualWhen the study began enrolling
Primary completion2027-05-27estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2027-05-27estimatedThe whole study's end, after follow-up
First posted2024-08-01actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2025-10-28actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Hypoparathyroidism

Interventions

  • Drug: 400 µg of MBX 2109 once-weekly by subcutaneous injection
  • Drug: 200-1600 µg of MBX 2109 once-weekly by subcutaneous injection

Primary outcome

what the primary-completion date above is the date OF
To evaluate the long-term safety and tolerability of weekly MBX 2109 in patients with hypoparathyroidism.
measured 104 weeks

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