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Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL

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NCT06500273 · readout ≤ 498 d

Sponsored by Allogene Therapeutics (industry) · ALLO — their whole pipeline →. With Foresight Diagnostics, Inc., Natera, Inc..

Phase
Phase 2
Status
Recruiting
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
250estimated
Sites
82
Countries
Australia, Canada, South Korea +1

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2024-06-18actualWhen the study began enrolling
Primary completionDec 2027estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completionDec 2032estimatedThe whole study's end, after follow-up
First posted2024-07-15actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-07-30actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Large B-cell Lymphoma

Interventions

  • Genetic: cemacabtagene ansegedleucel — also filed as cema-cel
  • Drug: Fludarabine — also filed as Fludara®
  • Drug: Cyclophosphamide — also filed as Cytoxan®
  • Device: Foresight CLARITY™ IUO MRD test, powered by PhasED-Seq™ — also filed as Foresight Lymphoma MRD Therapy Selection Test

Primary outcome

what the primary-completion date above is the date OF
Event-free survival per independent review committee assessment
measured Up to 60 months

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