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P2a Open Label Study to Evaluate 2-HPβCD in Subjects With Diabetic Kidney Disease

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NCT06489340

Sponsored by ZyVersa Therapeutics, Inc. (industry) · ZVSA — their whole pipeline →.

Phase
Phase 2
Status
Withdrawn
Study type
Interventional
Design
Na · None · Treatment
Enrollment
0actual
Sites
1
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Why the sponsor stopped it

Withdrawn due to patient enrollment challenges

As filed on the registry record, in the sponsor's own words.

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2025-06-11actualWhen the study began enrolling
Primary completion2026-08-11estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2026-08-11estimatedThe whole study's end, after follow-up
First posted2024-07-05actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2025-11-25actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Diabetic Kidney Disease

Intervention

  • Drug: 2HPβCD — also filed as 2-hydroxypropyl-β-cyclodextrin

Primary outcomes

what the primary-completion date above is the date OF
Percent change in 24-hour urinary albumin to creatinine ratio (UACR)
measured From Day 1 (baseline) to Week 12 (end of treatment)
Incidence of Treatment-Emergent Adverse Events (Safety and Tolerability)
measured 12 Weeks

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