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A Study to Evaluate Bioavailability of Rocatinlimab Autoinjector and Vial in Healthy Participants

← catalyst calendar

NCT06438263

Sponsored by Amgen (industry) · AMGN — their whole pipeline →.

Phase
Phase 1
Status
Completed
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
231actual
Sites
3
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2024-08-06actualWhen the study began enrolling
Primary completion2025-05-03actualThe date the last participant is measured for the primary outcome — the readout window
Study completion2025-07-02actualThe whole study's end, after follow-up
First posted2024-05-31actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-01-20actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Atopic Dermatitis

Interventions

  • Drug: Rocatinlimab — also filed as AMG 451
  • Drug: Rocatinlimab — also filed as AMG 451

Primary outcomes

what the primary-completion date above is the date OF
Maximum Plasma Concentration (Cmax) of Rocatinlimab
measured Up to approximately 112 days
Area Under the Serum Concentration-time Curve (AUC) From Time Zero to Time of Last Quantifiable Concentration (AUClast) of Rocatinlimab
measured Up to approximately 112 days
AUC From Time Zero to Infinity (AUCinf) of Rocatinlimab
measured Up to approximately 112 days

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