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A Non-interventional, Prospective Study With Benralizumab

← catalyst calendar

NCT06422078 · readout in 499 d

Sponsored by AstraZeneca (industry) · AZN — their whole pipeline →.

Phase
Status
Recruiting
Study type
Observational
Enrollment
300estimated
Sites
41
Country
Germany

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2024-07-25actualWhen the study began enrolling
Primary completion2027-12-31estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2027-12-31estimatedThe whole study's end, after follow-up
First posted2024-05-20actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-06-24actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Asthma, Bronchial

Primary outcomes

what the primary-completion date above is the date OF
Change in Asthma Control Test (ACT) total score in patients from baseline to week 12, 24 and 52 after first benralizumab dose
measured From baseline to week 12, 24 and 52
Proportion of responders at baseline, week 12, 24 and 52 after first benralizumab dose, using ACT
measured At baseline, week 12, 24 and 52
Change in daily doses of prescribed inhaled corticosteroids (ICS) intake from baseline to week 12, 24 and 52 after first benralizumab dose
measured From baseline to week 12, 24 and 52
Change in daily doses of patient-reported inhaled corticosteroids (ICS) intake from baseline to week 12, 24 and 52 after first benralizumab dose
measured From baseline to week 12, 24 and 52
Reduction (in percentage) in prescribed daily ICS dose intake from baseline to week 52 after first benralizumab dose
measured From baseline to week 52
Reduction (in percentage) in patient-reported daily ICS dose intake from baseline to week 52 after first benralizumab dose
measured From baseline to week 52

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